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Italian Association of Clinical Endocrinologists (AME) and Italian AACE Chapter Position Statement for Clinical Practice: Acromegaly - Part 1: Diagnostic and Clinical Issues
- Source :
- Endocrine, Metabolic & Immune Disorders Drug Targets
- Publication Year :
- 2020
- Publisher :
- Bentham Science Publishers Ltd., 2020.
-
Abstract
- Acromegaly is a rare disease. Improvements in lifespan in these patients have recently been reported due to transsphenoidal surgery (TSS), advances in medical therapy, and strict criteria for defining disease remission. This document reports the opinions of a group of Italian experts who have gathered together their prolonged clinical experience in the diagnostic and therapeutic challenges of acromegaly patients. Both GH and IGF-I (only IGF-I in those treated with Pegvisomant) are needed in the diagnosis and follow-up. Comorbidities (cardio-cerebrovascular disease, sleep apnea, metabolic derangement, neoplasms, and bone/joint disease) should be specifically addressed. Any newly diagnosed patient should be referred to a multidisciplinary team experienced in the treatment of pituitary adenomas.
- Subjects :
- Position statement
Pediatrics
medicine.medical_specialty
Endocrinology, Diabetes and Metabolism
medicine.medical_treatment
030209 endocrinology & metabolism
Disease
Article
NO
Comorbidities
03 medical and health sciences
0302 clinical medicine
Acromegaly
medicine
Humans
Immunology and Allergy
Insulin-Like Growth Factor I
LS4_3
Societies, Medical
Transsphenoidal surgery
Discrepant
Human Growth Hormone
business.industry
GH
IGF-I
Pituitary
Sleep apnea
medicine.disease
Clinical Practice
Endocrinologists
Italy
Practice Guidelines as Topic
Pegvisomant
business
030217 neurology & neurosurgery
medicine.drug
Rare disease
Subjects
Details
- ISSN :
- 18715303
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- Endocrine, Metabolic & Immune Disorders - Drug Targets
- Accession number :
- edsair.doi.dedup.....6b44d9f1e3e9b1c2a47e4a5971ca8c0a