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The feasibility of transoesophageal bioimpedance measurements for the detection of heart graft rejection
- Source :
- PHYSIOLOGICAL MEASUREMENT, r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau, instname, UPCommons. Portal del coneixement obert de la UPC, Universitat Politècnica de Catalunya (UPC), Recercat. Dipósit de la Recerca de Catalunya
- Publication Year :
- 2011
- Publisher :
- IOP PUBLISHING LTD, 2011.
-
Abstract
- Previous studies demonstrate that it is possible to evaluate a heart graft rejection condition using a bioimpedance technique by means of an intracavitary catheter. We propose to use a less invasive technique consisting in the use of a transoesophageal catheter and two standard ECG electrodes on the thorax. The aim of this work is to evaluate, using the finite element method, several parameters affecting the transoesophageal impedance measurement, including sensitivity to electrical conductivity and permittivity of different organs in the thorax, changes in magnitude and phase due to a lesion producing a scar, a global ischaemia of the heart, pleural effusion in the lungs, fat thickness increase, displacement of the catheter inside the oesophagus and movement of one electrode on the thorax surface. From these results, we deduce the best estimator for cardiac rejection detection and obtain the tools to identify eventual cases of false positives due to other factors. To achieve these objectives we have created a thoracic model and we have simulated different situations at the frequencies of 13, 30, 100, 300 and 1000 kHz. Our simulation demonstrates that the phase, at 100 and 300 kHz, would be a better estimator than the magnitude to evaluate a heart rejection condition.
- Subjects :
- Thorax
Graft Rejection
Male
Cor -- Trasplantació
Physiology
Pleural effusion
Finite Element Analysis
heart graft rejection
Biomedical Engineering
Biophysics
Less invasive
Myocardial Ischemia
FEM simulation
Models, Biological
Cicatrix
Motion
Esophagus
Physiology (medical)
bioimpedance
Electric Impedance
Medicine
Humans
Heart graft
Heart Atria
Electrodes
Enginyeria biomèdica::Electrònica biomèdica [Àrees temàtiques de la UPC]
business.industry
Focused Impedance Measurement
transoesophageal
Electric Conductivity
Reproducibility of Results
medicine.disease
Catheter
Bioimpedància
Feasibility Studies
Heart Transplantation
Female
business
Sensitivity (electronics)
Standard ECG
Biomedical engineering
Heart-- Transplantation -- Complications -- Imaging
Subjects
Details
- ISSN :
- 09673334
- Database :
- OpenAIRE
- Journal :
- PHYSIOLOGICAL MEASUREMENT, r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau, instname, UPCommons. Portal del coneixement obert de la UPC, Universitat Politècnica de Catalunya (UPC), Recercat. Dipósit de la Recerca de Catalunya
- Accession number :
- edsair.doi.dedup.....6b82bec8bcaa37cd2db7ee907dd7f8f7