Back to Search
Start Over
A High Burden of Asymptomatic Gastrointestinal Infections in Traditional Communities in Papua New Guinea
- Source :
- The American Journal of Tropical Medicine and Hygiene
- Publication Year :
- 2017
- Publisher :
- American Society of Tropical Medicine and Hygiene, 2017.
-
Abstract
- Stool samples were collected from 148 healthy adults living a traditional subsistence lifestyle in Papua New Guinea and screened for enteric pathogens using real-time RT-PCR/PCR assays. Enteric pathogens were detected in a high proportion (41%) of individuals. Clear differences were observed in the detection of pathogens between highland and lowland communities. In particular, there was a marked difference in detection rates of norovirus GII (20% and 0%, respectively) and Shigella sp. (15% and 0%, respectively). Analysis of the relationship between enteric pathogen carriage and microbial community composition of participants, using box plots to compare specific normal flora population numbers, did not suggest that gut microbial composition was directly associated with pathogen carriage. This study suggests that enteric pathogens are common in healthy individuals in Papua New Guinean highland communities, presumably acting as a reservoir of infection and thus contributing to a high burden of gastrointestinal illnesses.
- Subjects :
- Adult
Diarrhea
0301 basic medicine
Veterinary medicine
Gastrointestinal Diseases
Cross-sectional study
030106 microbiology
Population
Biology
Asymptomatic
Gastrointestinal infections
Enteropathogenic Escherichia coli
Feces
Papua New Guinea
03 medical and health sciences
0302 clinical medicine
Virology
parasitic diseases
medicine
Enterotoxigenic Escherichia coli
Humans
030212 general & internal medicine
education
Asymptomatic Infections
Pathogen
education.field_of_study
Helicobacter pylori
Norovirus
Gastrointestinal Microbiome
New guinea
Campylobacter
Articles
Cross-Sectional Studies
Infectious Diseases
Carriage
Parasitology
Shigella
medicine.symptom
Subjects
Details
- ISSN :
- 14761645 and 00029637
- Volume :
- 97
- Database :
- OpenAIRE
- Journal :
- The American Journal of Tropical Medicine and Hygiene
- Accession number :
- edsair.doi.dedup.....6b9c98cd57539e7472a753a8baa4e5d6
- Full Text :
- https://doi.org/10.4269/ajtmh.17-0282