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KRAS, NRAS, and BRAF mutations are highly enriched in trisomy 12 chronic lymphocytic leukemia and are associated with shorter treatment-free survival
- Source :
- Leukemia
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- not available
- Subjects :
- Male
Neuroblastoma RAS viral oncogene homolog
Chronic lymphocytic leukaemia
Cancer Research
Letter
Chronic lymphocytic leukemia
Trisomy
medicine.disease_cause
GTP Phosphohydrolases
GTP Phosphohydrolase
Adult
Aged
Female
Humans
Leukemia, Lymphocytic, Chronic, B-Cell
Membrane Proteins
Middle Aged
Proto-Oncogene Proteins B-raf
Proto-Oncogene Proteins p21(ras)
Chromosomes, Human, Pair 12
Mutation
0302 clinical medicine
hemic and lymphatic diseases
Pair 12
Medicine
Chronic
Cancer genetics
Membrane Protein
0303 health sciences
Leukemia
Event free survival
Hematology
Lymphocytic
Oncology
030220 oncology & carcinogenesis
KRAS
Human
Chromosomes
03 medical and health sciences
030304 developmental biology
Extramural
business.industry
B-Cell
Settore MED/15
medicine.disease
Cancer research
business
Subjects
Details
- ISSN :
- 14765551 and 08876924
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- Leukemia
- Accession number :
- edsair.doi.dedup.....6bd276d8d37848fdbb8bef6d1ef7a895
- Full Text :
- https://doi.org/10.1038/s41375-019-0444-6