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Primary hematological malignancy of the uterine cervix: A case report
- Source :
- Oncology Letters
- Publication Year :
- 2019
- Publisher :
- Spandidos Publications, 2019.
-
Abstract
- The present case report investigated the clinical characteristics of primary hematological malignancy of the uterine cervixin five patients. Among the five patients, three patients were diagnosed with non-Hodgkin's lymphoma (NHL) and two patients with myeloid sarcoma (MS) of the uterine cervix. Biopsies of the uterine cervices demonstrated the involvement of lymphoid cells or myeloid blasts cells. Immunohistochemical staining demonstrated the expression of B-lymphoid and myeloid lineage markers. The associated lysozyme, myeloperoxidase and mast/stem cell growth factor receptor (CD117) markers were specific for the diagnosis of MS. The three patients with NHL survived, and one of the patients survived for 82 months with no evidence of disease; however, was eventually lost to follow-up. The two patients with MS succumbed to the cancer as a result of progressive disease and leukemia. Therefore, pathological examination may be important for the timely diagnosis and appropriate therapeutic regimen for primary hematological malignancy of the uterine cervix.
- Subjects :
- non-Hodgkin's lymphoma
0301 basic medicine
Cancer Research
Pathology
medicine.medical_specialty
Myeloid
03 medical and health sciences
0302 clinical medicine
hemic and lymphatic diseases
myeloid sarcoma
Myeloid sarcoma
Medicine
biology
business.industry
CD117
Cancer
Articles
medicine.disease
Non-Hodgkin's lymphoma
Lymphoma
Leukemia
030104 developmental biology
medicine.anatomical_structure
Oncology
030220 oncology & carcinogenesis
biology.protein
primary hematological malignancy of the uterine cervix
business
Progressive disease
Subjects
Details
- ISSN :
- 17921082 and 17921074
- Database :
- OpenAIRE
- Journal :
- Oncology Letters
- Accession number :
- edsair.doi.dedup.....6be7e99887a1a40815ef7ff8e54cd29c