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CarGene: characterisation of sets of genes based on metabolic pathways analysis

Authors :
Jesús S. Aguilar-Ruiz
Isabel A. Nepomuceno-Chamorro
Domingo S. Rodriguez-Baena
Norberto Díaz-Díaz
Source :
International journal of data mining and bioinformatics. 5(5)
Publication Year :
2011

Abstract

The great amount of biological information provides scientists with an incomparable framework for testing the results of new algorithms. Several tools have been developed for analysing gene-enrichment and most of them are Gene Ontology-based tools. We developed a Kyoto Encyclopedia of Genes and Genomes (Kegg)-based tool that provides a friendly graphical environment for analysing gene-enrichment. The tool integrates two statistical corrections and simultaneously analysing the information about many groups of genes in both visual and textual manner. We tested the usefulness of our approach on a previous analysis (Huttenshower et al.). Furthermore, our tool is freely available (http://www.upo.es/eps/bigs/cargene.html).

Details

ISSN :
17485673
Volume :
5
Issue :
5
Database :
OpenAIRE
Journal :
International journal of data mining and bioinformatics
Accession number :
edsair.doi.dedup.....6bf041427dd9746e025265712fd71cb5