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Zinc in elderly people: effects of zinc supplementation on psychological dimensions in dependence of IL-6 -174 polymorphism: a Zincage study
- Source :
- Rejuvenation research. 11(2)
- Publication Year :
- 2008
-
Abstract
- Zinc is relevant for psychological dimensions, which are altered in zinc deficiency, as in aging. Since zinc deficiency and the beneficial effect of zinc supplementation may be related to genotypes of IL-6 -174 polymorphism, the main goal was to examine psychological dimensions in relationship to plasma zinc and genetic background of IL-6 in healthy elderly subjects, recruited in Italy, Greece, and Poland, before and after zinc supplementation. On the basis of IL-6 -174 polymorphism, significant restoration occurs for PSS, especially in Greece and Poland, less for MMSE and GDS, after zinc supplementation, suggesting zinc is important in reducing stress in elderly people.
- Subjects :
- Gerontology
Aging
Genotype
International Cooperation
Physiology
chemistry.chemical_element
Zinc
Cognition
Polymorphism (computer science)
medicine
Elderly people
Humans
Interleukin 6
Plasma zinc
Aged
Aged, 80 and over
Polymorphism, Genetic
biology
business.industry
Interleukin-6
Healthy elderly
Middle Aged
medicine.disease
Affect
chemistry
Dietary Supplements
biology.protein
Zinc deficiency
Geriatrics and Gerontology
business
Stress, Psychological
Subjects
Details
- ISSN :
- 15491684
- Volume :
- 11
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Rejuvenation research
- Accession number :
- edsair.doi.dedup.....6c0bcd7307a3c01e5c587fdd318fca3f