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Can Lung Ultrasound Be the Ideal Monitoring Tool to Predict the Clinical Outcome of Mechanically Ventilated COVID-19 Patients? An Observational Study

Authors :
Luigi Vetrugno
Francesco Meroi
Daniele Orso
Natascia D’Andrea
Matteo Marin
Gianmaria Cammarota
Lisa Mattuzzi
Silvia Delrio
Davide Furlan
Jonathan Foschiani
Francesca Valent
Tiziana Bove
Source :
Healthcare; Volume 10; Issue 3; Pages: 568
Publication Year :
2022
Publisher :
MDPI AG, 2022.

Abstract

Background: During the COVID-19 pandemic, lung ultrasound (LUS) has been widely used since it can be performed at the patient’s bedside, does not produce ionizing radiation, and is sufficiently accurate. The LUS score allows for quantifying lung involvement; however, its clinical prognostic role is still controversial. Methods: A retrospective observational study on 103 COVID-19 patients with respiratory failure that were assessed with an LUS score at intensive care unit (ICU) admission and discharge in a tertiary university COVID-19 referral center. Results: The deceased patients had a higher LUS score at admission than the survivors (25.7 vs. 23.5; p-value = 0.02; cut-off value of 25; Odds Ratio (OR) 1.1; Interquartile Range (IQR) 1.0−1.2). The predictive regression model shows that the value of LUSt0 (OR 1.1; IQR 1.0–1.3), age (OR 1.1; IQR 1.0−1.2), sex (OR 0.7; IQR 0.2−3.6), and days in spontaneous breathing (OR 0.2; IQR 0.1–0.5) predict the risk of death for COVID-19 patients (Area under the Curve (AUC) 0.92). Furthermore, the surviving patients showed a significantly lower difference between LUS scores at admission and discharge (mean difference of 1.75, p-value = 0.03). Conclusion: Upon entry into the ICU, the LUS score may play a prognostic role in COVID-19 patients with ARDS. Furthermore, employing the LUS score as a monitoring tool allows for evaluating the patients with a higher probability of survival.

Details

ISSN :
22279032
Volume :
10
Database :
OpenAIRE
Journal :
Healthcare
Accession number :
edsair.doi.dedup.....6c4b65f66e6e49d106e1f6df3ac00f5f
Full Text :
https://doi.org/10.3390/healthcare10030568