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Improvements to an optical scintillator imaging-based tissue dosimetry system
- Source :
- Journal of Biomedical Optics
- Publication Year :
- 2019
-
Abstract
- Previous work has shown that capturing optical emission from plastic discs attached directly to the skin can be a viable means to accurately measure surface dose during total skin electron therapy. This method can provide accurate dosimetric information rapidly and remotely without the need for postprocessing. The objective of this study was to: (1) improve the robustness and usability of the scintillators and (2) enhance sensitivity of the optical imaging system to improve scintillator emission detection as related to tissue surface dose. Baseline measurements of scintillator optical output were obtained by attaching the plastic discs to a flat tissue phantom and simultaneously irradiating and imaging them. Impact on underlying surface dose was evaluated by placing the discs on-top of the active element of an ionization chamber. A protective coating and adhesive backing were added to allow easier logistical use, and they were also subjected to disinfection procedures, while verifying that these changes did not affect the linearity of response with dose. The camera was modified such that the peak of detector quantum efficiency better overlapped with the emission spectra of the scintillating discs. Patient imaging was carried out and surface dose measurements were captured by the updated camera and compared to those produced by optically stimulated luminescence detectors (OSLD). The updated camera was able to measure surface dose with3 % difference compared to OSLD–Cherenkov emission from the patient was suppressed and scintillation detection was enhanced by 25 × and 7 × , respectively. Improved scintillators increase underlying surface dose on average by 5.2 ± 0.1 % and light output decreased by 2.6 ± 0.3 % . Disinfection had0.02 % change on scintillator light output. The enhanced sensitivity of the imaging system to scintillator optical emission spectrum can now enable a reduction in physical dimensions of the dosimeters without loss in ability to detect light output.
- Subjects :
- Paper
Materials science
Optically stimulated luminescence
Biomedical Engineering
medical imaging
Dose profile
Scintillator
01 natural sciences
010309 optics
Biomaterials
Optics
optical devices
0103 physical sciences
Medical imaging
Image Processing, Computer-Assisted
Dosimetry
Humans
Gamma Cameras
Whole Body Imaging
General
Scintillation
scintillation
business.industry
Phantoms, Imaging
Detector
Optical Imaging
radiation oncology
Equipment Design
Atomic and Molecular Physics, and Optics
Electronic, Optical and Magnetic Materials
biomedical optics
Ionization chamber
Scintillation Counting
business
camera
Subjects
Details
- ISSN :
- 15602281
- Volume :
- 24
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Journal of biomedical optics
- Accession number :
- edsair.doi.dedup.....6c80bc744e5e2f1f87466d873f166225