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The renal patient seen by non-renal physicians: the kidney embedded in the 'milieu intérieur'
- Source :
- Clinical Kidney Journal
- Publication Year :
- 2020
-
Abstract
- Chronic kidney disease is defined as a decrease in renal function or evidence of kidney injury for >3 months. This represents an oversimplification that may confuse physicians. Thus kidney function is equated to glomerular filtration rate, which represents one of multiple kidney functions. Some potentially more important renal functions are lost earlier, such as the production for the anti-ageing factor Klotho. Overall, these changes modify the emergent properties of the body, altering the relationships between different organs and systems, in a manner that is difficult to predict the response to interventions based on normal physiology concepts, as there is a novel steady state of interorgan relations. In this regard we now discuss the impact of CKD on heart failure; osteomuscular and joint pain and bone fragility and fractures; and osteosarcopaenia as seen by a cardiologist, a rheumatologist and a geriatrician. ispartof: CLINICAL KIDNEY JOURNAL vol:14 issue:4 pages:1077-1087 ispartof: location:England status: published
- Subjects :
- medicine.medical_specialty
BASE-LINE
Renal function
heart failure
network disease
030204 cardiovascular system & hematology
Bone fragility
DISEASE
SARCOPENIA
03 medical and health sciences
0302 clinical medicine
QUALITY-OF-LIFE
OSTEOPOROTIC FRACTURES
medicine
emergence
Milieu intérieur
030212 general & internal medicine
OLDER-PEOPLE
Intensive care medicine
AcademicSubjects/MED00340
Klotho
CKJ Reviews
Transplantation
Kidney
Science & Technology
business.industry
osteosarcopaenia
Urology & Nephrology
MUSCLE
medicine.disease
bone fragility
medicine.anatomical_structure
POSTMENOPAUSAL WOMEN
Nephrology
fracture
Joint pain
Heart failure
HEART-FAILURE
medicine.symptom
BONE-MINERAL DENSITY
business
Life Sciences & Biomedicine
chronic kidney disease
Kidney disease
Subjects
Details
- ISSN :
- 20488505
- Volume :
- 14
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Clinical kidney journal
- Accession number :
- edsair.doi.dedup.....6cfd8ce8a66a6b5b3fa64573ab3f37fb