Back to Search Start Over

Combined approaches to identify genomic regions involved in phenotypic differentiation between low divergent breeds: Application in Sardinian sheep populations

Authors :
Elena Ciani
Gianluca Sottile
Fabio Pilla
Baldassare Portolano
Slim Ben Jemaa
Sara Casu
Salvatore Mastrangelo
Mastrangelo S.
Ben Jemaa S.
Sottile G.
Casu S.
Portolano B.
Ciani E.
Pilla F.
Source :
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und ZuchtungsbiologieREFERENCES. 136(6)
Publication Year :
2019

Abstract

Selective breeding has led to modifications in the genome of many livestock breeds. In this study, we identified the genomic regions that may explain some of the phenotypic differences between two closely related breeds from Sardinia. A total of 44 animals, 20 Sardinian Ancestral Black (SAB) and 24 Sardinian White (SW), were genotyped using the Illumina Ovine 50K array. A total of 68, 38 and 15 significant markers were identified using the case–control genome-wide association study (GWAS), the Bayesian population differentiation analysis (FST) and the Rsb metric, respectively. Comparisons among the approaches revealed a total of 22 overlapping markers between GWAS and FST and one marker between GWAS and Rsb. Three markers detected by Rsb were also located near (

Details

ISSN :
14390388
Volume :
136
Issue :
6
Database :
OpenAIRE
Journal :
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und ZuchtungsbiologieREFERENCES
Accession number :
edsair.doi.dedup.....6d8d7ef0392a11d45aa87ed49520c1cc