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The development of arthritis and antinuclear antibodies correlate with serum 25-hydroxyvitamin D levels in patients with leprosy

Authors :
Carlos Eduardo Ferreira
Eliane Aparecida Rosseto
Cristóvão Luis Pitangueira Mangueira
Helena Lúcia Alves Pereira
Sandra Lúcia Euzébio Ribeiro
Morton Scheinberg
Source :
Annals of the Rheumatic Diseases. 71:2062-2063
Publication Year :
2012
Publisher :
BMJ, 2012.

Abstract

Leprosy, a chronic granulomatous infection, presents with cutaneous and neurological manifestations. Musculoskeletal involvement, though the third most common manifestation, is underdiagnosed.1 ,2 In its natural history, other immune manifestations besides articular manifestations may be present, such as the presence of autoantibodies.3 ,4 There is evidence that vitamin D influences the activity of immune-mediated diseases, particularly autoimmune diseases.5 ,6 Amazon is a state in the northern part of Brazil where the disease is endemic. It has a high level of sunshine, so a low prevalence of vitamin D insufficiency would be expected. In this study we looked at the serum vitamin D …

Details

ISSN :
14682060 and 00034967
Volume :
71
Database :
OpenAIRE
Journal :
Annals of the Rheumatic Diseases
Accession number :
edsair.doi.dedup.....6e0a8b9f6191ba69ff13dec517f56b8f
Full Text :
https://doi.org/10.1136/annrheumdis-2012-201485