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The development of arthritis and antinuclear antibodies correlate with serum 25-hydroxyvitamin D levels in patients with leprosy
- Source :
- Annals of the Rheumatic Diseases. 71:2062-2063
- Publication Year :
- 2012
- Publisher :
- BMJ, 2012.
-
Abstract
- Leprosy, a chronic granulomatous infection, presents with cutaneous and neurological manifestations. Musculoskeletal involvement, though the third most common manifestation, is underdiagnosed.1 ,2 In its natural history, other immune manifestations besides articular manifestations may be present, such as the presence of autoantibodies.3 ,4 There is evidence that vitamin D influences the activity of immune-mediated diseases, particularly autoimmune diseases.5 ,6 Amazon is a state in the northern part of Brazil where the disease is endemic. It has a high level of sunshine, so a low prevalence of vitamin D insufficiency would be expected. In this study we looked at the serum vitamin D …
- Subjects :
- Arthritis, Infectious
Endemic Diseases
Anti-nuclear antibody
business.industry
Immunology
Arthritis
Disease
medicine.disease
General Biochemistry, Genetics and Molecular Biology
Natural history
Immune system
Rheumatology
Antibodies, Antinuclear
Leprosy
Vitamin D and neurology
medicine
Humans
Immunology and Allergy
Vitamin D
Serum 25 hydroxyvitamin d
business
Brazil
Subjects
Details
- ISSN :
- 14682060 and 00034967
- Volume :
- 71
- Database :
- OpenAIRE
- Journal :
- Annals of the Rheumatic Diseases
- Accession number :
- edsair.doi.dedup.....6e0a8b9f6191ba69ff13dec517f56b8f
- Full Text :
- https://doi.org/10.1136/annrheumdis-2012-201485