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Supplementary Figure 4 from Bispecific Antibodies Enable Synthetic Agonistic Receptor-Transduced T Cells for Tumor Immunotherapy

Authors :
Sebastian Kobold
Christian Klein
Stefan Endres
Claudio Sustmann
Gerhard Niederfellner
Peter Duewell
Jian Ding
Daniel Lamp
Martin Jastroch
Johannes vom Berg
Ramona Murr
Constanze Heise
Stefanie Lesch
Bruno L. Cadilha
Felicitas Rataj
Martina Geiger
Richard Klaus
Mathias Kurzay
Moritz L. Schmidbauer
Mohamed-Reda Benmebarek
Clara H. Karches
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplementary Figure 4: Human SAR T cells are specifically stimulated by anti-human mesothelin x anti-EGFRv3 2 + 1 BiAb and redirect lysis to mesothelin+ target cells in vitro and in vivo

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....6e39997f7c43ba5db9abe24ffdb8d671
Full Text :
https://doi.org/10.1158/1078-0432.22474304.v1