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Feasibility of forced oscillatory assessment of respiratory mechanics across a laryngeal mask airway in rabbits
- Source :
- Physiological Measurement, Vol. 40, No 6 (2019) P. 065001
- Publication Year :
- 2019
-
Abstract
- OBJECTIVES The forced oscillation technique (FOT) is the method of choice for assessment of respiratory tissue mechanics. A laryngeal mask airway (LMA) is increasingly used to secure the airways in subjects under sedation or general anesthesia. While FOT is routinely performed using an endotracheal tube (ETT), the accuracy of information about airway and tissue mechanics obtained with FOT using a LMA has not been characterized. Therefore, we compared the mechanical parameters obtained with FOT using LMA and ETT in rabbits. APPROACH FOT was performed through a LMA at normal and reduced oscillatory amplitudes in anesthetized and mechanically ventilated rabbits (n = 9) at positive end-expiratory pressures (PEEP) of 3 and 6 cmH2O. These measurements were repeated at normal amplitude for the same animal using an ETT. Airway resistance, inertance, respiratory tissue damping (G) and elastance (H) were measured under each condition by FOT. The potential bias of the distensible upper airways when FOT was applied using LMA was assessed with a simulation study. MAIN RESULTS Values of parameters reflecting airway mechanics were significantly higher when measured using LMA at both PEEPs and oscillatory amplitudes than with ETT. Conversely, regardless of the condition, there was a correlation (r = 0.89 both at normal and reduced amplitudes; p
- Subjects :
- Male
Physiology
0206 medical engineering
Biomedical Engineering
Biophysics
02 engineering and technology
Respiratory physiology
Laryngeal Masks
03 medical and health sciences
0302 clinical medicine
Airway resistance
Forced Oscillation Technique
Laryngeal mask airway
Physiology (medical)
Intubation, Intratracheal
Medicine
Animals
Computer Simulation
Respiratory system
Lung
ddc:617
business.industry
Airway Resistance
respiratory system
020601 biomedical engineering
respiratory tract diseases
Inertance
Anesthesia
Respiratory Mechanics
Feasibility Studies
Female
Rabbits
Airway
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 13616579 and 09673334
- Volume :
- 40
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Physiological measurement
- Accession number :
- edsair.doi.dedup.....6e4b531edeafbd89795d10546dd332c3