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Control of transplant tolerance and intragraft regulatory T cell localization by CCL5

Authors :
Claire Usal
Bernard Vanhove
Bernard Martinet
Gilles Blancho
Nahzli Dilek
Nicolas Poirier
BMC, Ed.
Immunointervention dans les allo et xénotransplantations
Université de Nantes (UN)-IFR26-Institut National de la Santé et de la Recherche Médicale (INSERM)-ITUN
Source :
Journal of Translational Medicine, Vol 10, Iss Suppl 3, p P60 (2012), Journal of Translational Medicine, 7th European Workshop on Immune-Mediated Inflammatory Diseases, 7th European Workshop on Immune-Mediated Inflammatory Diseases, Nov 2012, Netherlands. pp.P60
Publication Year :
2012
Publisher :
BMC, 2012.

Abstract

Material, methods and results In rat recipients of kidney allografts where tolerance was induced by costimulation blockade, we observed a 2-fold decrease of plasma CCL5 levels as compared to control syngeneic grafted animals (0.60 ± 0.17 vs. 1.17 ± 0.48 ng/ml; p

Details

Language :
English
ISSN :
14795876
Volume :
10
Database :
OpenAIRE
Journal :
Journal of Translational Medicine
Accession number :
edsair.doi.dedup.....6e74a36f6d347e5b20d4886734cb93e8