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Novel duck hepatitis A virus type 1 isolates from adult ducks showing egg drop syndrome
- Source :
- Veterinary microbiology. 221
- Publication Year :
- 2018
-
Abstract
- Generally, duck hepatitis A virus type 1 (DHAV-1) only infects young ducklings. Since December 2016, severe outbreaks of duck viral infection with egg drop, feed consumption decline, and ovary-oviduct disease have occurred in some laying duck flocks in Shandong Province of China. DHAV-1 isolated from the affected ducks was confirmed as the causative pathogen of the egg drop. Compared with other DHAV-1 strains, the novel isolate has three special amino acid mutation points in the most variable regions at the C-terminus of VP1. The experimental infection in laying ducks indicated that successful immunization with DHAV-1 vaccine could protect laying duck from infection. To the best of our knowledge, this is the first reported incidence of a severe duck disease outbreak involving egg drop syndrome caused by DHAV-1.
- Subjects :
- 0301 basic medicine
Veterinary medicine
China
animal structures
Feed consumption
040301 veterinary sciences
animal diseases
viruses
Oviposition
Oviducts
Biology
Microbiology
Disease Outbreaks
0403 veterinary science
03 medical and health sciences
Amino acid mutation
medicine
Animals
Egg drop syndrome
Pathogen
Duck hepatitis A virus
Phylogeny
Poultry Diseases
General Veterinary
Laying duck
virus diseases
Outbreak
04 agricultural and veterinary sciences
General Medicine
Hepatitis A
medicine.disease
030104 developmental biology
Ducks
Female
Flock
Hepatitis A virus
Subjects
Details
- ISSN :
- 18732542
- Volume :
- 221
- Database :
- OpenAIRE
- Journal :
- Veterinary microbiology
- Accession number :
- edsair.doi.dedup.....6f06fc2e4d52f6283171b1ae2903f050