Back to Search
Start Over
Use of serum circulating CCNB2 in cancer surveillance
- Source :
- The International journal of biological markers. 25(4)
- Publication Year :
- 2010
-
Abstract
- Cyclin B2 (CCNB2), a member of the cyclin protein family, has been found to be up-regulated in human cancers. To evaluate the potential use of circulating CCNB2 in serum in cancer surveillance, we examined relative expression levels of serum circulating CCNB2 mRNA in 103 cancer patients, 19 normal controls, and 40 benign disease patients using real-time quantitative reverse transcriptase polymerase chain reaction. We found that the relative expression level of circulating CCNB2 mRNA in cancer patients was significantly higher (p
- Subjects :
- Male
Transcriptional Activation
0301 basic medicine
Cancer Research
medicine.medical_specialty
Lung Neoplasms
Genital Neoplasms, Female
Clinical Biochemistry
Digestive System Neoplasms
Gastroenterology
Pathology and Forensic Medicine
law.invention
Metastasis
03 medical and health sciences
0302 clinical medicine
law
Neoplasms
Internal medicine
Biomarkers, Tumor
medicine
Humans
Cyclin B2
RNA, Messenger
Polymerase chain reaction
Aged
Cyclin
Messenger RNA
Lung
Receiver operating characteristic
business.industry
Area under the curve
Cancer
Middle Aged
medicine.disease
030104 developmental biology
medicine.anatomical_structure
Urinary Bladder Neoplasms
Oncology
Case-Control Studies
030220 oncology & carcinogenesis
Female
business
Subjects
Details
- ISSN :
- 17246008
- Volume :
- 25
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- The International journal of biological markers
- Accession number :
- edsair.doi.dedup.....6fdcc0bc9d32f7bd0914de1e14b6a3f4