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Physical Function in Middle-aged and Older Adults with Type 1 Diabetes: Long-term Follow-up of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study

Authors :
the DCCT/EDIC Research Group
William H. Herman
Rose Gubitosi-Klug
Alan M. Jacobson
John M. Lachin
Ionut Bebu
Barbara H. Braffett
Pearl Lee
Jye-Yu C. Backlund
Victoria R. Trapani
Catherine L. Martin
Publication Year :
2022
Publisher :
American Diabetes Association, 2022.

Abstract

Objective: To describe the prevalence and clinical correlates of functional limitations in middle-aged and older adults with long-standing type 1 diabetes. Research Design and Methods: Functional limitations were assessed for 1,094 participants in the Epidemiology of Diabetes Interventions and Complications (EDIC) study, a multi-center, longitudinal, observational follow-up of participants with type 1 diabetes randomly assigned to intensive or conventional diabetes therapy during the Diabetes Control and Complications Trial (DCCT). The primary outcome measure was a score . Results: Fifty-three percent of participants were male. The mean age was 59.5±6.8 years and mean diabetes duration was 37.9±4.9 years. The prevalence of SPPB score Conclusions: Almost half of the middle-aged and older adults with long-standing type 1 diabetes reported functional limitations, which were associated with higher HbA1c and BMI, general psychological distress, and cardiac autonomic neuropathy. Future research is needed to determine if these findings are generalizable.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....6fea2d2dc983250f52b9690c87088d3e
Full Text :
https://doi.org/10.2337/figshare.20198807.v1