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Higher body mass index at ages 16 to 20 years is associated with increased risk of a multiple sclerosis diagnosis in subsequent adulthood among men
- Source :
- Multiple Sclerosis Journal. 27:147-150
- Publication Year :
- 2020
- Publisher :
- SAGE Publications, 2020.
-
Abstract
- Background: Evidence for the association between body mass index (BMI) and multiple sclerosis (MS) among men remains mixed. Objective and methods: Swedish military conscription and other registers identified MS after age of 20 years and BMI at ages 16–20 years ( N = 744,548). Results: Each unit (kg/m2) BMI increase was associated with greater MS risk (hazard ratio and 95% confidence interval = 1.034, 1.016–1.053), independent of physical fitness (1.021, 1.001–1.042). Categorised, overweight and obesity were associated with statistically significant raised MS risk compared to normal weight, but not after adjustment for physical fitness. Conclusion: MS risk rises with increasing BMI, across the entire BMI range.
- Subjects :
- Adult
Male
medicine.medical_specialty
Pediatrics
Multiple Sclerosis
Neurology
Adolescent
Body Mass Index
Young Adult
03 medical and health sciences
0302 clinical medicine
Risk Factors
0502 economics and business
medicine
Humans
Obesity
business.industry
Multiple sclerosis
05 social sciences
Overweight
medicine.disease
Increased risk
Physical Fitness
050211 marketing
Neurology (clinical)
Underweight
medicine.symptom
business
Body mass index
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 14770970 and 13524585
- Volume :
- 27
- Database :
- OpenAIRE
- Journal :
- Multiple Sclerosis Journal
- Accession number :
- edsair.doi.dedup.....707cb37534a7db54dd84e5f6128e9155