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Pathologic assessment of vasculopathies in pulmonary hypertension
- Source :
- Journal of the American College of Cardiology. 43:S25-S32
- Publication Year :
- 2004
- Publisher :
- Elsevier BV, 2004.
-
Abstract
- Pulmonary arterial hypertension (PAH) includes various forms of pulmonary hypertension of different etiology but similar clinical presentation and functional derangement. Histopathological vascular changes in all forms of PAH are qualitatively similar but with quantitative differences in the distribution and prevalence of pathological changes in various portions of the pulmonary vascular bed. The documentation of these topographic variations in the response of the pulmonary vasculature to injury may be important to understand the pathogenesis of the various subsets of PAH. To standardize the precise histopathological documentation of the pulmonary vasculopathy in PAH we propose a histopathological classification that includes both the predominant segment of the pulmonary vasculature affected and the possible coexistence of pathological changes in other vascular segments.
- Subjects :
- Pulmonary Circulation
Pathology
medicine.medical_specialty
Vascular disease
business.industry
Hypertension, Pulmonary
Respiratory disease
Pulmonary capillary hemangiomatosis
Pulmonary Artery
medicine.disease
Pulmonary hypertension
Muscle, Smooth, Vascular
Vasoconstriction
Pulmonary venoocclusive disease
Circulatory system
medicine
Humans
Vascular Resistance
Vascular Diseases
Pulmonary Veno-Occlusive Disease
Pulmonary pathology
Tunica Intima
Cardiology and Cardiovascular Medicine
business
Lung
Subjects
Details
- ISSN :
- 07351097
- Volume :
- 43
- Database :
- OpenAIRE
- Journal :
- Journal of the American College of Cardiology
- Accession number :
- edsair.doi.dedup.....707fbb7f0fa05373c62be773ba8342df