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Proteomic profile of Ostrea edulis haemolymph in response to bonamiosis and identification of candidate proteins as resistance markers
Proteomic profile of Ostrea edulis haemolymph in response to bonamiosis and identification of candidate proteins as resistance markers
- Source :
- Diseases of aquatic organisms. 128(2)
- Publication Year :
- 2018
-
Abstract
- European flat oyster Ostrea edulis populations have suffered extensive mortalities caused by bonamiosis. The protozoan parasite Bonamia ostreae is largely responsible for this disease in Europe, while its congener B. exitiosa has been detected more recently in various European countries. Both of these intracellular parasites are able to survive and proliferate within haemocytes, the main cellular effectors of the immune system in molluscs. Two-dimensional electrophoresis was used to compare the haemolymph protein profile between Bonamia spp.-infected and non-infected oysters within 3 different stocks, a Galician stock of oysters selected for resistance against bonamiosis, a non-selected Galician stock and a selected Irish stock. Thirty-four proteins with a presumably relevant role in the oyster-Bonamia spp. interaction were identified; they were involved in major metabolic pathways, such as energy production, respiratory chain, oxidative stress, signal transduction, transcription, translation, protein degradation and cell defence. Furthermore, the haemolymph proteomic profiles of the non-infected oysters of the 2 Galician stocks were compared. As a result, 7 proteins representative of the non-infected Galician oysters selected for resistance against bonamiosis were identified; these 7 proteins could be considered as candidate markers of resistance to bonamiosis, which should be further assessed.
- Subjects :
- 0301 basic medicine
Proteomics
Oyster
animal structures
Hemocytes
Haplosporida
Respiratory chain
Zoology
Aquatic Science
Protein degradation
Host-Parasite Interactions
03 medical and health sciences
Bonamia ostreae
biology.animal
Hemolymph
Ostrea
Animals
Ostrea edulis
Ecology, Evolution, Behavior and Systematics
Shellfish
Proteomic Profile
biology
04 agricultural and veterinary sciences
biology.organism_classification
030104 developmental biology
Gene Expression Regulation
040102 fisheries
0401 agriculture, forestry, and fisheries
Bonamia
Subjects
Details
- ISSN :
- 01775103
- Volume :
- 128
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Diseases of aquatic organisms
- Accession number :
- edsair.doi.dedup.....70fbad5755e043a04a606e7093c1cf68