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Management trends and outcomes of breast angiosarcoma: Is breast conservation feasible?
Management trends and outcomes of breast angiosarcoma: Is breast conservation feasible?
- Source :
- The Breast Journal. 25:1230-1234
- Publication Year :
- 2019
- Publisher :
- Hindawi Limited, 2019.
-
Abstract
- We queried the National Cancer Database for nonmetastatic breast angiosarcoma, yielding 808 patients (202 de novo, 606 secondary). The median survival was 53.7 months. Secondary tumors were more likely to undergo mastectomy than de novo lesions (OR = 3.99, P 0.001). Treatments included lumpectomy (10%), lumpectomy/radiation (3%), mastectomy alone (73%), or mastectomy/radiation (14%), with no difference in survival (P = 0.68). Lumpectomy correlated with positive margin rate (OR 3.29), which was a predictor for death (HR = 2.37, P 0.01), along with older age, higher comorbidity scores, size5 cm, and high-grade disease (P 0.05). While breast angiosarcoma is usually treated with mastectomy, lumpectomy may be feasible for well-selected tumors.
- Subjects :
- Oncology
medicine.medical_specialty
medicine.medical_treatment
Hemangiosarcoma
Breast Neoplasms
Disease
Mastectomy, Segmental
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Risk Factors
Internal medicine
Internal Medicine
medicine
Humans
Aged
Neoplasm Staging
Breast conservation
business.industry
Patient Selection
Lumpectomy
Age Factors
Cancer
Breast angiosarcoma
Middle Aged
medicine.disease
United States
Patient Care Management
Tumor Burden
030220 oncology & carcinogenesis
Female
Radiotherapy, Adjuvant
Surgery
Secondary tumors
Neoplasm Grading
business
Organ Sparing Treatments
Median survival
Mastectomy
Subjects
Details
- ISSN :
- 15244741 and 1075122X
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- The Breast Journal
- Accession number :
- edsair.doi.dedup.....713bfa472d8436d786cff15878267424
- Full Text :
- https://doi.org/10.1111/tbj.13439