Back to Search
Start Over
Perioperative Complications in Endoscopic Endonasal versus Transcranial Resections of Adult Craniopharyngiomas
- Source :
- World neurosurgery. 152
- Publication Year :
- 2021
-
Abstract
- Background Adult craniopharyngiomas are low-grade tumors of the pituitary infundibulum that can be locally aggressive and frequently present with profound visual deficits and endocrinopathies. Surgical resection remains the preferred initial treatment for these lesions, and recently endoscopic endonasal approaches (EEAs) have become increasingly used. However, minimal data exist comparing these techniques with traditional transcranial (TC) methods. The purpose of this study was to evaluate perioperative differences in EEA and TC approaches for adult craniopharyngiomas over the past several decades. Methods Craniopharyngioma surgeries in the Nationwide Inpatient Sample from 1998 to 2014 were identified. Complication rates, mortality rates, and annual treatment trends were stratified by procedure. Annual caseload was assessed with linear regression, and multivariate logistic regression models were created to determine predictors of inpatient mortality and perioperative complications. Results From 1998−2014, a significant increase in EEAs for craniopharyngiomas (+4.36/year, r2 = 0.80, P Conclusions Over the past several decades, utilization of EEAs to resect adult craniopharyngiomas has increased. EEAs appear to be associated with lower rates of perioperative mortality and complications. However, long-term, prospective studies controlling for tumor size, location, and preoperative symptomatology are needed to determine when one approach should be used preferentially over the other.
- Subjects :
- Adult
Male
Natural Orifice Endoscopic Surgery
medicine.medical_specialty
medicine.medical_treatment
Nose
Logistic regression
Craniopharyngioma
Postoperative Complications
medicine
Humans
Pituitary Neoplasms
Prospective cohort study
Craniotomy
Tumor size
business.industry
Mortality rate
Perioperative
Middle Aged
medicine.disease
Surgery
Neuroendoscopy
Female
Neurology (clinical)
Complication
business
Subjects
Details
- ISSN :
- 18788769
- Volume :
- 152
- Database :
- OpenAIRE
- Journal :
- World neurosurgery
- Accession number :
- edsair.doi.dedup.....7165b0c6f989254c65d726d30638b0f1