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Postpartum Severe Sinus Bradycardia following Methylergonovine Administration
- Source :
- Journal of International Medical Research. 36:1129-1133
- Publication Year :
- 2008
- Publisher :
- SAGE Publications, 2008.
-
Abstract
- The case is reported of a 30-year-old multigravida, with insignificant history and stable vital signs, admitted to the labour room for normal vaginal delivery of twins. She received combined spinal epidural analgesia (bupivacaine plus fentanyl) for 3 h. Following uneventful delivery she received 0.2 mg methylergonovine maleate, intramuscularly. Nausea and vomiting occurred 70 min after placenta delivery, heart rate decreased, arterial blood pressure increased and there was chest pain. After excluding cardiac ischaemia, 0.5 mg atropine sulphate was administered intravenously. Chest pain improved but heart rate and blood pressure increased more than expected. The patient had mild headache and nausea, and antiemetic 4 mg ondansetron was given intravenously. Continuous monitoring for 4 h showed spontaneous chest pain relief and blood pressure improvement. In conclusion, serious delayed side-effects arising from methylergonovine maleate can occur in young, normal patients and close monitoring is required. Intravenous atropine sulphate following methylergonovine maleate administration may lead to severe hypertension and tachycardia.
- Subjects :
- Adult
Bradycardia
medicine.medical_specialty
Chest pain
Biochemistry
Ondansetron
Electrocardiography
Methylergonovine
Pregnancy
Oxytocics
medicine
Humans
Methylergonovine Maleate
Bupivacaine
business.industry
Biochemistry (medical)
Cell Biology
General Medicine
Surgery
Blood pressure
Anesthesia
Vomiting
Analgesia, Obstetrical
Female
medicine.symptom
business
medicine.drug
Subjects
Details
- ISSN :
- 14732300 and 03000605
- Volume :
- 36
- Database :
- OpenAIRE
- Journal :
- Journal of International Medical Research
- Accession number :
- edsair.doi.dedup.....7188a58979dfaa527d90b9c460a403bd
- Full Text :
- https://doi.org/10.1177/147323000803600534