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Transformable upconversion metal–organic frameworks for near-infrared light-programmed chemotherapy
- Source :
- Chemical Communications. 57:7826-7829
- Publication Year :
- 2021
- Publisher :
- Royal Society of Chemistry (RSC), 2021.
-
Abstract
- A transformable upconversion MOF comprising a UCNP core and an azobenzene-based MOF shell is designed for NIR light-modulated chemotherapy. The dual Förster resonance energy transfers (FRETs) involved in this delivery system trigger the transformation of the MOF for drug release and prodrug activation, thus significantly inhibiting the tumor growth and metastasis.
- Subjects :
- Materials science
Cell Survival
Infrared Rays
Energy transfer
Antineoplastic Agents
Nanotechnology
02 engineering and technology
010402 general chemistry
01 natural sciences
Catalysis
Mice
chemistry.chemical_compound
Drug Delivery Systems
Cell Line, Tumor
Fluorescence Resonance Energy Transfer
Materials Chemistry
Animals
Prodrugs
Tumor growth
Particle Size
Metal-Organic Frameworks
Cell Proliferation
Near infrared light
Molecular Structure
fungi
Metals and Alloys
General Chemistry
Prodrug
021001 nanoscience & nanotechnology
Photon upconversion
0104 chemical sciences
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Azobenzene
chemistry
Ceramics and Composites
Female
Metal-organic framework
Delivery system
Drug Screening Assays, Antitumor
0210 nano-technology
Subjects
Details
- ISSN :
- 1364548X and 13597345
- Volume :
- 57
- Database :
- OpenAIRE
- Journal :
- Chemical Communications
- Accession number :
- edsair.doi.dedup.....725adb5d1589e8d9e17b8ecc16b08711