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Biomedical Relevance of Novel Anticancer Peptides in the Sensitive Treatment of Cancer
- Source :
- Biomolecules, Biomolecules, Vol 11, Iss 1120, p 1120 (2021)
- Publication Year :
- 2021
-
Abstract
- The global increase in cancer mortality and economic losses necessitates the cautious quest for therapeutic agents with compensatory advantages over conventional therapies. Anticancer peptides (ACPs) are a subset of host defense peptides, also known as antimicrobial peptides, which have emerged as therapeutic and diagnostic candidates due to several compensatory advantages over the non-specificity of the current treatment regimens. This review aimed to highlight the ravaging incidence of cancer, the use of ACPs in cancer treatment with their mechanisms, ACP discovery and delivery methods, and the limitations for their use. This would create awareness for identifying more ACPs with better specificity, accuracy and sensitivity towards the disease. It would also promote their efficacious utilization in biotechnology, medical sciences and molecular biology to ease the severity of the disease and enable the patients living with these conditions to develop an accommodating lifestyle.
- Subjects :
- 0301 basic medicine
anticancer peptides
peptide delivery
Antimicrobial peptides
Antineoplastic Agents
Disease
Review
host-defense peptides
Bioinformatics
Biochemistry
Microbiology
03 medical and health sciences
Delivery methods
0302 clinical medicine
Cell Line, Tumor
Neoplasms
Drug Discovery
medicine
Humans
cancer
Amino Acid Sequence
Molecular Targeted Therapy
Molecular Biology
Cancer mortality
business.industry
Treatment regimen
Cell Membrane
apoptosis
Cancer
medicine.disease
QR1-502
Cancer treatment
030104 developmental biology
030220 oncology & carcinogenesis
cytolysis
business
Antimicrobial Cationic Peptides
Subjects
Details
- ISSN :
- 2218273X
- Volume :
- 11
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Biomolecules
- Accession number :
- edsair.doi.dedup.....726c853475c02c73ab46b7378a7c327f