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Unmet need in rheumatology: reports from the Targeted Therapies meeting 2018
- Source :
- Annals of the rheumatic diseases. 78(7)
- Publication Year :
- 2018
-
Abstract
- To develop a comprehensive listing of the greatest unmet scientific and clinical needs in rheumatology. The 20th annual international Targeted Therapies meeting brought more than 100 leading basic scientists and clinical researchers in rheumatology, immunology, epidemiology, molecular biology and other specialties. During the meeting, breakout sessions were convened, consisting of five disease-specific groups with 20–30 experts assigned to each group based on expertise. Specific groups included rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis, systemic lupus erythematosus, connective tissue diseases and a basic science immunology group spanning all of these clinical domains. In each group, experts were asked to consider recent accomplishments within their clinical domain in the last year and update the unmet needs in three categorical areas: basic/translational science, clinical science and therapeutic development, and clinical care. While progress was noted among some of previously identified needs, both new needs were identified and themes from prior meetings were re-iterated: the need for better understanding the heterogeneity within each disease, and for identifying preclinical states of disease allowing treatment and prevention of disease in those at risk, and the elusive ability to cure disease. Within the clinical care realm, improved comorbidity management and patient-centred care continue to be unmet needs, and the need for new and affordable therapeutics was highlighted. Unmet needs for new and accessible targeted therapies, disease prevention and ultimately cure remain a priority in rheumatology.
- Subjects :
- 0301 basic medicine
Research design
medicine.medical_specialty
Immunology
Disease
General Biochemistry, Genetics and Molecular Biology
03 medical and health sciences
Psoriatic arthritis
0302 clinical medicine
Rheumatology
Internal medicine
Rheumatic Diseases
Epidemiology
medicine
Immunology and Allergy
Humans
030203 arthritis & rheumatology
Health Services Needs and Demand
business.industry
Congresses as Topic
medicine.disease
Comorbidity
030104 developmental biology
Family medicine
Antirheumatic Agents
Needs assessment
Translational science
business
Subjects
Details
- ISSN :
- 14682060
- Volume :
- 78
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Annals of the rheumatic diseases
- Accession number :
- edsair.doi.dedup.....72727c8d1b5a942d03c6c2bb0e9e89f3