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OpenABM-Covid19-An agent-based model for non-pharmaceutical interventions against COVID-19 including contact tracing
- Source :
- PLoS Computational Biology, Vol 17, Iss 7, p e1009146 (2021), PLoS Computational Biology
- Publication Year :
- 2021
- Publisher :
- Public Library of Science (PLoS), 2021.
-
Abstract
- SARS-CoV-2 has spread across the world, causing high mortality and unprecedented restrictions on social and economic activity. Policymakers are assessing how best to navigate through the ongoing epidemic, with computational models being used to predict the spread of infection and assess the impact of public health measures. Here, we present OpenABM-Covid19: an agent-based simulation of the epidemic including detailed age-stratification and realistic social networks. By default the model is parameterised to UK demographics and calibrated to the UK epidemic, however, it can easily be re-parameterised for other countries. OpenABM-Covid19 can evaluate non-pharmaceutical interventions, including both manual and digital contact tracing, and vaccination programmes. It can simulate a population of 1 million people in seconds per day, allowing parameter sweeps and formal statistical model-based inference. The code is open-source and has been developed by teams both inside and outside academia, with an emphasis on formal testing, documentation, modularity and transparency. A key feature of OpenABM-Covid19 are its Python and R interfaces, which has allowed scientists and policymakers to simulate dynamic packages of interventions and help compare options to suppress the COVID-19 epidemic.<br />Author summary Throughout the COVID-19 pandemic, computational modelling has been used to inform key uncertainties facing policymakers such as the number of cases and deaths, hospital capacity, tests and contact tracers. Models need to be: sufficiently complex to yield realistic predictions; computationally efficient to allow calibrations; and easy to use so that various policy mixes can be evaluated. OpenABM-Covid19 is a detailed epidemic model of the spread of COVID-19, simulating every individual in a population. Our model enables scientists and policymakers to quickly compare the effectiveness of non-pharmaceutical interventions like lockdowns, testing, quarantine, and digital and manual contact tracing. The model considers a hypothetical city with a default population of 1 million people whose ages and contact patterns are parameterised according to UK demographics. All of the parameters are openly documented and modifiable so that they can be adapted to fit other countries’ data, and refined to match our understanding of COVID-19 as the epidemic progresses. The computer model simulates people’s movement between their homes, workplaces, schools, and social interactions. OpenABM-Covid19 is open source and has been developed collaboratively by teams from academia and industry. Its modularity, documentation, testing framework, and accessibility via Python and R have provided validation, invited contributions, and encouraged wide adoption.
- Subjects :
- 0301 basic medicine
Viral Diseases
Systems Analysis
Epidemiology
Computer science
Inference
Geographical locations
Disease Outbreaks
COVID-19 Testing
Medical Conditions
0302 clinical medicine
Documentation
Epidemiological Statistics
Medicine and Health Sciences
Public and Occupational Health
Biology (General)
Virus Testing
Agent-based model
Vaccines
education.field_of_study
Computational model
Ecology
Vaccination and Immunization
Europe
Infectious Diseases
England
Computational Theory and Mathematics
Risk analysis (engineering)
Modeling and Simulation
Transparency (graphic)
Quarantine
Epidemiological Methods and Statistics
Research Article
COVID-19 Vaccines
Infectious Disease Control
QH301-705.5
Physical Distancing
Immunology
Population
Modularity
Infectious Disease Epidemiology
03 medical and health sciences
Cellular and Molecular Neuroscience
Diagnostic Medicine
Genetics
Humans
European Union
education
Molecular Biology
Ecology, Evolution, Behavior and Systematics
SARS-CoV-2
COVID-19
Biology and Life Sciences
Covid 19
United Kingdom
030104 developmental biology
Systems analysis
Age Groups
People and Places
Population Groupings
Preventive Medicine
Contact Tracing
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- ISSN :
- 15537358
- Volume :
- 17
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- PLoS Computational Biology
- Accession number :
- edsair.doi.dedup.....728975c47c00afa102d70ba2acd71d9a