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Strategic vision for improving human health at The Forefront of Genomics

Authors :
Paul P. Liu
Allison Mandich
Chris Gunter
Elise A. Feingold
Adam Felsenfeld
Teri A. Manolio
Valentina Di Francesco
Kris A. Wetterstrand
Daniel L. Kastner
Leslie G. Biesecker
Jyoti G. Dayal
Britny J. Kish
Vence L. Bonham
Anastasia L. Wise
Elaine A. Ostrander
William A. Gahl
Benjamin D. Solomon
Susan Vasquez
William J. Pavan
Laura Lyman Rodriguez
David J. Kaufman
Carla Easter
Lawrence C. Brody
Adam M. Phillippy
Sarah A. Bates
Eric D. Green
Christopher Wellington
Carolyn M. Hutter
Bettie J. Graham
Darryl Leja
Source :
Nature
Publication Year :
2020
Publisher :
Springer Science and Business Media LLC, 2020.

Abstract

Starting with the launch of the Human Genome Project three decades ago, genomics has become progressively entrenched within the bedrock of the biomedical research enterprise. Capitalizing on the momentum of the project’s successful completion in 2003, genomics now regularly plays a central and catalytic role in basic and translational research, and studies increasingly demonstrate the vital role that genomic information can play in clinical care. Looking ahead, the anticipated advances in technology development, biological insights, and clinical applications (among others) will lead to more widespread integration of genomics into virtually all areas of biomedical research, the adoption of genomics into mainstream medical and public-health practices, and an increasing relevance of genomics in everyday life. On behalf of the research community, the National Human Genome Research Institute recently completed a multi-year process of strategic engagement to capture input about the future research priorities and opportunities in human genomics, with an emphasis on health applications. Here we articulate the highest-priority elements envisioned for the cutting-edge of human genomics going forward – that is, at “The Forefront of Genomics.”

Details

Language :
English
ISSN :
14764687 and 00280836
Database :
OpenAIRE
Journal :
Nature
Accession number :
edsair.doi.dedup.....729b9133bb22a05ced505b98f2a268d4
Full Text :
https://doi.org/10.1038/s41586-020-2817-4