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Effect of Nepeta bracteata Benth. on allergic rhinitis symptoms: A randomized double-blind clinical trial
- Source :
- Journal of Research in Medical Sciences, Vol 22, Iss 1, Pp 128-128 (2017), Journal of Research in Medical Sciences : The Official Journal of Isfahan University of Medical Sciences
- Publication Year :
- 2017
- Publisher :
- Wolters Kluwer Medknow Publications, 2017.
-
Abstract
- Background: Allergic rhinitis (AR) is one of the health problems in the world. It is necessary to develop new treatment procedure for control of this disease. The aim of this study was to assess the effect of Zofa (Nepeta bracteata Benth) on AR patients. Materials and Methods: In this double-blind randomized clinical trial study, 71 patients (37 patients in treatment and 34 in placebo group) participated. In treatment group, N. bracteata syrup (NBS) was used for 4 weeks as three times a day. The efficacy of the drug regarding AR symptoms (rhinorrhea, sneezing, nasal obstruction, itchy nose, and ocular symptoms) were evaluated through a visual analog scale (VAS) by 0–10 before administration and at the end of the whole treatment period. The collected information was entered in the SPSS software (version 18) and was analyzed using the Fisher's exact test, Chi-square test, independent sample t-test, and paired sample test. Results: The improvement of AR symptoms in the group receiving NBS was significantly higher compared to control group (4.73 ± 1.84 vs. 0.38 ± 2.06; P < 0.0001). Furthermore, the mean of total VAS before and after the treatment (in case group) was 7.10 ± 1.92 and 2.37 ± 1.76, respectively (P < 0.001). Conclusion: The results of this study indicate that N. bracteata has significant effects on improving the symptoms of AR. Hence, it can be a good alternative to AR symptoms relief.
- Subjects :
- medicine.medical_specialty
Visual analogue scale
lcsh:Medicine
Allergic rhinitis
law.invention
Double blind
Nepeta bracteata Benth
03 medical and health sciences
0302 clinical medicine
Randomized controlled trial
law
Internal medicine
Nepeta
medicine
030212 general & internal medicine
Nose
rhinorrhea
biology
business.industry
lcsh:R
General Medicine
biology.organism_classification
Persian medicine
Clinical trial
Exact test
medicine.anatomical_structure
030228 respiratory system
Original Article
medicine.symptom
business
Subjects
Details
- Language :
- English
- ISSN :
- 17357136 and 17351995
- Volume :
- 22
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of Research in Medical Sciences
- Accession number :
- edsair.doi.dedup.....72b988f865230fdd303f2c783be1511b