Additional file 5 of The quorum sensing peptide EntF* promotes colorectal cancer metastasis in mice: a new factor in the host-microbiome interaction

Additional file 5: Figure S1. Verification of the LC1-MS1 method. Figure S2. qPCR detection of EntF. Figure S3. Effect of EntF* and EntF* analogues on E-cadherin expression. Figure S4. Representative images of Western blot analyses. Figure S5. Overview of E-cadherin-regulating pathways. Figure S6. In vivo effects of the Phr0662 quorum sensing peptide in an orthotopic mouse model of colorectal cancer. Table S1. Concentration of EntF* in mice serum measured using the LC1-MS1 method and confirmation of the results using additional chromatographic method and qPCR. Table S2. Synopsis of known receptors involved in E-cadherin downregulation, their natural ligands, natural ligands’ active domains and alignment scores with EntF* peptide. Table S3. Presence of EntF gene and peptide in different E. faecium strains. Table S4. Histopathological scoring system.