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Correction: Long-term outcome of smear-positive tuberculosis patients after initiation and completion of treatment: A ten-year retrospective cohort study
- Source :
- PLoS ONE, PLoS ONE, Vol 13, Iss 4, p e0196432 (2018)
- Publication Year :
- 2018
- Publisher :
- Public Library of Science, 2018.
-
Abstract
- Background The status of tuberculosis (TB) patients since initiation of treatment is unknown in South Ethiopia. The objective of this study was to assess the long-term outcomes of smear-positive TB patients since initiation and completion of treatment, which includes TB recurrence and mortality of TB patients. Methods We did a retrospective cohort study on 2,272 smear-positive TB patients who initiated treatment for TB from September 1, 2002—October 10, 2012 in health facilities in Dale district and Yirgalem town administration. We followed them from the date of start of treatment to either the date of interview or date of death. Results Recurrence rate of TB was 15.2 per 1000 person-years. Recurrence was higher for re-treatment cases (adjusted hazard ratio (aHR), 2.7; 95% CI, 1.4–5.3). Mortality rate of TB patients was 27.1 per 1,000 person-years. The risk was high for patients above 34 years of age (aHR, 2.1; 95% CI, 1.2–3.9), poor patients (aHR, 1.3; 95% CI, 1.0–1.8), patients with poor treatment outcomes (aHR, 6.7; 95% CI, 5.1–8.9) and for patients treated at least 3 times (aHR 4.8; 95% CI, 2.1–11.1). The excess mortality occurred among patients aged above 34 years was high (41.2/1000 person years). Conclusion High TB recurrence and death of TB patients was observed among our study participants. Follow-up of TB patients with the risk factors and managing them could reduce the TB burden.
- Subjects :
- 0301 basic medicine
Adult
Male
medicine.medical_specialty
Tuberculosis
Adolescent
030106 microbiology
Treatment outcome
Antitubercular Agents
lcsh:Medicine
03 medical and health sciences
Young Adult
0302 clinical medicine
Tuberculosis diagnosis
Recurrence
Risk Factors
Internal medicine
Medicine
Humans
030212 general & internal medicine
Young adult
Mortality
lcsh:Science
Child
Retrospective Studies
Excess mortality
Multidisciplinary
business.industry
Mortality rate
Hazard ratio
lcsh:R
Correction
Infant
Retrospective cohort study
medicine.disease
Treatment Outcome
Child, Preschool
lcsh:Q
Female
Ethiopia
Health Facilities
business
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 13
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....74673c2388dc8568cfa921df2876bee6