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Expression profiling of Wnt signaling genes during gonadal differentiation and gametogenesis in rainbow trout
- Source :
- Sexual Development, Sexual Development, Karger, 2011, 5 (6), pp.318-329. ⟨10.1159/000334515⟩
- Publication Year :
- 2011
-
Abstract
- Wnt signaling plays major roles in various processes, including ovarian differentiation and development in mammals. In order to explore its potential implication during gonadal development in a nonmammalian vertebrate species, expression of Wnt signaling genes was investigated in rainbow trout during gonadal differentiation and gametogenesis. Multiple Wnt pathway genes were expressed and exhibited distinct expression patterns. In ovary, tcf7 was highly expressed during early differentiation, whereas no sexually dimorphic expression of rspo1 was detected. During later ovarian development, wnt11 was highly expressed in granulosa cells and oocytes suggesting an implication in folliculogenesis and oogenesis, whereas wnt9b was principally detected in granulosa cells. In testis, Wnt pathway genes were mostly expressed during early spermatogenesis. Overall, these present results suggest that Wnt signaling is implicated in multiple processes of male and female gonadal development and provide basis for future studies on Wnt signaling functions in teleost fish gonads.
- Subjects :
- Male
Embryology
medicine.medical_specialty
endocrine system
gamétogenèse
Sex Differentiation
Endocrinology, Diabetes and Metabolism
[SDV]Life Sciences [q-bio]
Ovary
Biology
Real-Time Polymerase Chain Reaction
Oogenesis
Gametogenesis
03 medical and health sciences
0302 clinical medicine
Internal medicine
Testis
medicine
Animals
RSPO1
Wnt Signaling Pathway
In Situ Hybridization
030304 developmental biology
teleost fish
0303 health sciences
Sexual differentiation
urogenital system
Wnt signaling pathway
rainbow trout
Wnt signaling
GENOMIQUE
Cell biology
Gene expression profiling
Endocrinology
medicine.anatomical_structure
030220 oncology & carcinogenesis
Oncorhynchus mykiss
Female
Development of the gonads
Developmental Biology
SALMONIDE
Subjects
Details
- ISSN :
- 16615433 and 16615425
- Volume :
- 5
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation
- Accession number :
- edsair.doi.dedup.....7475c8fa68394532f932af8669b353f2