Back to Search
Start Over
Plant autophagy is responsible for peroxisomal transition and plays an important role in the maintenance of peroxisomal quality
- Source :
- Autophagy, Autophagy, Taylor & Francis, 2014, 10 (5), pp.936-937. ⟨10.4161/auto.28529⟩
- Publication Year :
- 2014
- Publisher :
- HAL CCSD, 2014.
-
Abstract
- In photosynthetic cells, a large amount of hydrogen peroxide is produced in peroxisomes through photorespiration, which is a metabolic pathway related to photosynthesis. Hydrogen peroxide, a reactive oxygen species, oxidizes peroxisomal proteins and membrane lipids, resulting in a decrease in peroxisomal quality. We demonstrate that the autophagic system is responsible for the elimination of oxidized peroxisomes in plant. We isolated Arabidopsis mutants that accumulated oxidized peroxisomes, which formed large aggregates. We revealed that these mutants were defective in autophagy-related (ATG) genes and that the aggregated peroxisomes were selectively targeted by the autophagic machinery. These findings suggest that autophagy plays an important role in the quality control of peroxisomes by the selective degradation of oxidized peroxisomes. In addition, the results suggest that autophagy is also responsible for the functional transition of glyoxysomes to leaf peroxisomes.
- Subjects :
- 0106 biological sciences
Arabidopsis thaliana
Membrane lipids
[SDV]Life Sciences [q-bio]
Arabidopsis
hydrogen peroxide
01 natural sciences
03 medical and health sciences
Glyoxysome
Autophagy
Peroxisomes
peroxisome
Molecular Biology
030304 developmental biology
chemistry.chemical_classification
0303 health sciences
Reactive oxygen species
biology
glyoxysome leaf peroxisome
Cell Biology
Peroxisome
Plants, Genetically Modified
biology.organism_classification
pexophagy
Autophagic Punctum
Cell biology
Plant Leaves
Metabolic pathway
Biochemistry
chemistry
Photorespiration
peroxisome transition
Reactive Oxygen Species
Oxidation-Reduction
Metabolic Networks and Pathways
010606 plant biology & botany
Subjects
Details
- Language :
- English
- ISSN :
- 15548627 and 15548635
- Database :
- OpenAIRE
- Journal :
- Autophagy, Autophagy, Taylor & Francis, 2014, 10 (5), pp.936-937. ⟨10.4161/auto.28529⟩
- Accession number :
- edsair.doi.dedup.....7494bf13147beb05b9f8653644efd908