Toxic Epidermal Necrolysis : A Case Report

oxic Epidermal Necrolysis (TEN) is a rare lifethreatening disorder characterised by extensivenecrolysis and detachment of full thickness epidermis,generally induced by drugs [1]. First described in 1939,the condition was named as TEN by Lyell in 1956.Separation of the dermal-epidermal junction causesNikolsky’s sign and gives skin the typical “wet dressing”appearance. The condition is self-limiting, with significantmorbidity rate (10-70%) and numerous sequelae maydevelop due to scarring [2]. Controversy persists aboutits definition, aetiopathogenesis and treatment [3].Corticosteroids have been the mainstay of therapy.Cyclosporin introduced into the treatment of TEN in1986 has been recently used in India.