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DESTAF: A database of text-mined associations for reproductive toxins potentially affecting human fertility
- Source :
- Reproductive Toxicology. 33:99-105
- Publication Year :
- 2012
- Publisher :
- Elsevier BV, 2012.
-
Abstract
- The Dragon Exploration System for Toxicants and Fertility (DESTAF) is a publicly available resource which enables researchers to efficiently explore both known and potentially novel information and associations in the field of reproductive toxicology. To create DESTAF we used data from the literature (including over 10 500 PubMed abstracts), several publicly available biomedical repositories, and specialized, curated dictionaries. DESTAF has an interface designed to facilitate rapid assessment of the key associations between relevant concepts, allowing for a more in-depth exploration of information based on different gene/protein-, enzyme/metabolite-, toxin/chemical-, disease- or anatomically centric perspectives. As a special feature, DESTAF allows for the creation and initial testing of potentially new association hypotheses that suggest links between biological entities identified through the database. DESTAF, along with a PDF manual, can be found at http://cbrc.kaust.edu.sa/destaf . It is free to academic and non-commercial users and will be updated quarterly.
- Subjects :
- Male
Human fertility
Databases, Factual
Reproductive toxicology
Interface (Java)
Computer science
Toxicology
computer.software_genre
Risk Assessment
Field (computer science)
User-Computer Interface
Resource (project management)
Risk Factors
Software Design
Databases, Genetic
Cluster Analysis
Data Mining
Humans
Database
Reproduction
Rapid assessment
Systems Integration
Fertility
Gene Expression Regulation
Developmental toxicology
Female
computer
Subjects
Details
- ISSN :
- 08906238
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- Reproductive Toxicology
- Accession number :
- edsair.doi.dedup.....74e0ea043dddc75e83179023f3775352