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Synthesis of bifunctional carbon quantum dots for bioimaging and anti-inflammation
- Source :
- Nanotechnology. 31:175102
- Publication Year :
- 2020
- Publisher :
- IOP Publishing, 2020.
-
Abstract
- Carbon quantum dots (CDs) have attracted increased attention in recent decades because of their various applications in biosensing, bioimaging and drug delivery. In the present study, we have synthesized bifunctional ibuprofen-based carbon quantum dots (ICDs) using a simple one-step microwave-assisted method, for simultaneous bioimaging and anti-inflammatory effects. The ICDs exhibited high stability, low toxicity, negligible cytotoxicity and good biocompatibility in water. In particular, the produced ICDs demonstrated a decent imaging ability and excellent anti-inflammatory effects in vivo, making them potentially useful in bioimaging and future clinical treatment. Our results demonstrated that ICDs show promise in applications such as multifunctional biomaterials, depending on the selection of carbon sources, which would provide important guidance for the future design of multifunctional CDs in the field of biomedicine.
- Subjects :
- Male
Materials science
Biocompatibility
Ibuprofen
Bioengineering
Nanotechnology
02 engineering and technology
Carrageenan
010402 general chemistry
01 natural sciences
Mice
chemistry.chemical_compound
Drug Stability
Quantum Dots
Animals
Humans
General Materials Science
Electrical and Electronic Engineering
Microwaves
Bifunctional
Clinical treatment
Inflammation
Low toxicity
Mechanical Engineering
Anti-Inflammatory Agents, Non-Steroidal
Anti inflammation
General Chemistry
021001 nanoscience & nanotechnology
Carbon
Molecular Imaging
0104 chemical sciences
Disease Models, Animal
chemistry
Mechanics of Materials
Carbon quantum dots
Drug delivery
Molecular imaging
0210 nano-technology
HeLa Cells
Subjects
Details
- ISSN :
- 13616528 and 09574484
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- Nanotechnology
- Accession number :
- edsair.doi.dedup.....74fab758b40a1b5dcdb566959c8cbd03