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Clinical impact of additional therapy for residual pancreatic cancer

Authors :
Fuminori Sonohara
Mitsuro Kanda
Kenta Murotani
Mitsuru Tashiro
Tsutomu Fujii
Chie Tanaka
Daisuke Kobayashi
Hideki Takami
Masahiko Koike
Yasuhiro Kodera
Suguru Yamada
Goro Nakayama
Masamichi Hayashi
Source :
Surgery Today. 50:440-448
Publication Year :
2019
Publisher :
Springer Science and Business Media LLC, 2019.

Abstract

This study aimed to explore the prognostic significance of the resection margin (R) status of pancreatic ductal adenocarcinoma (PDAC) patients receiving neoadjuvant therapy (NAT) or adjuvant chemotherapy (AC). We retrospectively reviewed 427 consecutive patients, and the overall survival (OS) and disease-free survival (DFS) were analyzed based on the R status by a propensity score analysis (PSA). The R0 ratio of the NAT (+) group was significantly higher than that of the NAT (−) group (97.2% vs. 69.6%, P

Details

ISSN :
14362813 and 09411291
Volume :
50
Database :
OpenAIRE
Journal :
Surgery Today
Accession number :
edsair.doi.dedup.....751cfd94d0668ed9aae549a9e8052150
Full Text :
https://doi.org/10.1007/s00595-019-01900-y