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Clinical impact of additional therapy for residual pancreatic cancer
- Source :
- Surgery Today. 50:440-448
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- This study aimed to explore the prognostic significance of the resection margin (R) status of pancreatic ductal adenocarcinoma (PDAC) patients receiving neoadjuvant therapy (NAT) or adjuvant chemotherapy (AC). We retrospectively reviewed 427 consecutive patients, and the overall survival (OS) and disease-free survival (DFS) were analyzed based on the R status by a propensity score analysis (PSA). The R0 ratio of the NAT (+) group was significantly higher than that of the NAT (−) group (97.2% vs. 69.6%, P
- Subjects :
- medicine.medical_specialty
Neoplasm, Residual
Additional Therapy
medicine.medical_treatment
030230 surgery
Gastroenterology
03 medical and health sciences
Pancreatectomy
0302 clinical medicine
Surgical oncology
Internal medicine
Pancreatic cancer
medicine
Humans
Propensity Score
Neoadjuvant therapy
Retrospective Studies
business.industry
Hazard ratio
Margins of Excision
General Medicine
medicine.disease
Combined Modality Therapy
Neoadjuvant Therapy
Pancreatic Neoplasms
Survival Rate
Chemotherapy, Adjuvant
Nat
030220 oncology & carcinogenesis
Propensity score matching
Resection margin
Surgery
business
Carcinoma, Pancreatic Ductal
Subjects
Details
- ISSN :
- 14362813 and 09411291
- Volume :
- 50
- Database :
- OpenAIRE
- Journal :
- Surgery Today
- Accession number :
- edsair.doi.dedup.....751cfd94d0668ed9aae549a9e8052150
- Full Text :
- https://doi.org/10.1007/s00595-019-01900-y