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Association between the diagnosis-to-treatment interval and overall survival in Taiwanese patients with oral cavity squamous cell carcinoma
- Source :
- European journal of cancer (Oxford, England : 1990). 72
- Publication Year :
- 2016
-
Abstract
- Background To investigate the association between the diagnosis-to-treatment interval (DTI) and overall survival (OS) in patients with oral cavity squamous cell carcinoma (OSCC). Methods A total of 18,677 patients with first primary OSCC identified in the Taiwanese Cancer Registry Database between 2004 and 2010 were examined. The effect of DTI on 5-year OS rates was investigated with multivariate Cox regression analysis. After the identification of the optimal cutoff for DTI based on the 5-year OS rates, DTI was classified in the following 20-day groups: ≤20 days (57% of the study patients), 21–45 days (34%), 46–90 days (6%) and ≥91 days (3%). In additional exploratory analyses, DTI was reclassified in the following 30-day interval groups: ≤30 days (81% of the study patients), 31–60 days (14%), 61–90 days (2%) and ≥91 days (3%). Results Multivariate analyses identified DTI (≤20 days versus other subgroups), sex (female versus male), age (
- Subjects :
- Adult
Male
Cancer Research
medicine.medical_specialty
Multivariate analysis
Adolescent
Treatment interval
Taiwan
Gastroenterology
Time-to-Treatment
03 medical and health sciences
Young Adult
0302 clinical medicine
Internal medicine
medicine
Overall survival
Humans
030212 general & internal medicine
Oral Cavity Squamous Cell Carcinoma
Stage (cooking)
Child
Aged
Proportional Hazards Models
Retrospective Studies
Aged, 80 and over
Proportional hazards model
business.industry
Hazard ratio
Middle Aged
Prognosis
Surgery
Cancer registry
Survival Rate
Oncology
030220 oncology & carcinogenesis
Carcinoma, Squamous Cell
Female
Mouth Neoplasms
business
Subjects
Details
- ISSN :
- 18790852
- Volume :
- 72
- Database :
- OpenAIRE
- Journal :
- European journal of cancer (Oxford, England : 1990)
- Accession number :
- edsair.doi.dedup.....75504aea69843a445b8c5f94e2ac4cc9