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Re-evaluating positive serum samples for SARS-CoV-2-specific IgA and IgG antibodies using an in-house serological assay

Authors :
Flavio De Maio
Melinda Mariotti
Brunella Posteraro
Francesca Bugli
Maurizio Sanguinetti
Margherita Cacaci
Rosalba Ricci
Grazia Angela Morandotti
Giulia Menchinelli
Riccardo Torelli
Source :
Clinical Microbiology and Infection
Publication Year :
2021
Publisher :
Elsevier BV, 2021.

Abstract

This letter takes a cue from a recently published study, which looked at diagnostic tests currently available for SARS-CoV-2 infection, to present and discuss the results of a re-evaluation of 122 positive serum samples from COVID-19 patients using an in-house serological assay for SARSCoV-2 antibodies detection. While serology targeting the SARS-CoV-2 S protein should be preferable, IgA testing is proposed in all situations for which serology is the solely practicable diagnostic strategy for SARSCoV-2 infection.

Details

ISSN :
1198743X
Volume :
27
Database :
OpenAIRE
Journal :
Clinical Microbiology and Infection
Accession number :
edsair.doi.dedup.....75ceb2ce6bd32011ba7ae9728d3e525f
Full Text :
https://doi.org/10.1016/j.cmi.2020.12.014