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Mortality in premature mice at birth and during neonatal development
- Publication Year :
- 1983
- Publisher :
- HAL CCSD, 1983.
-
Abstract
- This paper reports a statistical study of mortality in about 2 500 premature mice at birth and during neonatal development. The premature mice were removed by caesarean section and reanimated for 30 min.; surviving mice as well as newborns delivered vaginally on day 20 of pregnancy (control mice) were raised from birth to day 20 by nursing mothers spontaneously delivered at the same time. The mortality rate in the premature mice and control newborns was estimated immediately after birth by caesarean section and 30 min. after reanimation or parturition, 6 h after birth and at 9 h every day from neonatal days 2 to 20. The caesarean section did not cause mortality. The chances of the survival of premature mice at birth depended on both gestational age and birth weight. Premature mice could not survive if their gestational age was less than 19 days and their birth weight less than 33% of that of newborn mice at term. There was no relationship between mortality and the number of newborns per litter. Two types of mortality were observed in premature mice, mortality at reanimation and breeding mortality. Mortality at reanimation was about 13%; breeding mortality, occurring only during the first 3 neonatal days, was of two types: primary neonatal mortality (10.9%), occurring from the end of reanimation up to 6 h after birth, and secondary neonatal mortality (6.9%) which appeared from days 2 to 3. The role of some factors causing mortality has been discussed.
- Subjects :
- Litter (animal)
Embryology
medicine.medical_specialty
Time Factors
medicine.medical_treatment
Birth weight
Medicine (miscellaneous)
Gestational Age
Biology
Body weight
Mice
[SDV.BDD] Life Sciences [q-bio]/Development Biology
medicine
Animals
Caesarean section
Mortality
[SDV.BDLR] Life Sciences [q-bio]/Reproductive Biology
Pregnancy
Neonatal mortality
Obstetrics
Mortality rate
Body Weight
Gestational age
medicine.disease
[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition
Reproductive Medicine
Animals, Newborn
Immunology
Animal Science and Zoology
Developmental Biology
Food Science
Subjects
Details
- Language :
- French
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....760a0b897d8f3a9fe4f81b45f7be30f2