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The solid-phase synthesis of alpha-melanotropin
- Source :
- International journal of protein research. 3(4)
- Publication Year :
- 1971
-
Abstract
- The tridecapeptide amide, α-melanotropin, has been synthesized by the solid-phase method. The protected tridecapeptide was cleaved from a phenolic resin with ammonia, and the amide was reduced with sodium in liquid ammonia. Chromatographic purification gave the highly purified and fully active hormone.
- Subjects :
- Electrophoresis
Chromatography
Chemical Phenomena
Sodium
Alpha Melanotropin
chemistry.chemical_element
Esters
General Medicine
Amides
Chromatography, DEAE-Cellulose
chemistry.chemical_compound
Ammonia
Chemistry
Solid-phase synthesis
chemistry
Amide
Liquid ammonia
Organic chemistry
Melanocyte-Stimulating Hormones
Peptides
Resins, Plant
Subjects
Details
- ISSN :
- 00207551
- Volume :
- 3
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- International journal of protein research
- Accession number :
- edsair.doi.dedup.....762a6bb4cffca0c3c25cc946350b7ad2