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Laser-induced photo-polymerisation for creation of paper-based fluidic devices
- Source :
- Lab Chip. 14:4567-4574
- Publication Year :
- 2014
- Publisher :
- Royal Society of Chemistry (RSC), 2014.
-
Abstract
- Paper-based microfluidics is a rapidly progressing inter-disciplinary technology driven by the need for low-cost alternatives to conventional point-of-care diagnostic tools. For transport of reagents/analytes, such devices often consist of interconnected hydrophilic fluid-flow channels that are demarcated by hydrophobic barrier walls that extend through the thickness of the paper. Here, we present a laser-based fabrication procedure that uses polymerisation of a photopolymer to produce the required fluidic channels in paper. Experimental results showed that the structures successfully guide the flow of fluids and allow containment of fluids in wells, and hence the technique is suitable for fabrication of paper-based microfluidic devices. The minimum width for the hydrophobic barriers that successfully prevented fluid leakage was ~120 μm and the minimum width for the fluidic channels that can be formed was ~80 μm, the smallest reported so far for paper-based fluidic patterns.
- Subjects :
- Paper
Engineering
Fabrication
Microfluidics
Biomedical Engineering
Bioengineering
Nanotechnology
Diagnostic tools
Biochemistry
Polymerization
law.invention
Fluid leakage
law
Fluidics
Cellulose
business.industry
Lasers
Equipment Design
General Chemistry
Paper based
Microfluidic Analytical Techniques
Photochemical Processes
Laser
business
Hydrophobic and Hydrophilic Interactions
Subjects
Details
- ISSN :
- 14730189 and 14730197
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- Lab Chip
- Accession number :
- edsair.doi.dedup.....768c740aaeea702db4ac035446a23887