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High-dose-rate interstitial brachytherapy for mobile tongue cancer: preliminary results of a dose reduction trial

Authors :
Kimishige Shimizutani
Ken Yoshida
Takumi Arika
Hideya Yamazaki
Eiichi Tanaka
Koji Masui
Yasuo Yoshioka
Tadayuki Kotsuma
Hironori Akiyama
Tadashi Takenaka
Source :
Journal of Contemporary Brachytherapy
Publication Year :
2014
Publisher :
Termedia Publishing House, 2014.

Abstract

Purpose: To compare the outcome of our facility with another about the shortened schedule (60 Gy in 10 fractions to 54 Gy in 9 fractions) of high-dose-rate interstitial brachytherapy (HDR ISBT) for mobile tongue cancer. Material and methods: Eighteen patients were treated with HDR ISBT as a monotherapy in dose reduction schedule with some unique technique to determine the border of tumor accuracy (lugol’s staining and metal marker), and to minimize adverse effect (lead-lined silicon block) at our facility. Results: The 2-year local and regional control rates and cause-specific survival rate were 82%, 80%, and 83% and moderate to severe late complications occurred in five patients (28%), which were almost the same treatment results achieved by another facility. Conclusions: We recommend 54 Gy in 9 fractions over 7 days as a feasible treatment to reduce patient discomfort in mobile tongue cancer patients. J Contemp Brachytherapy 2014; 6, 1: 10–14 DOI: 10.5114/jcb.2014.40726

Details

Language :
English
ISSN :
20812841 and 1689832X
Volume :
6
Issue :
1
Database :
OpenAIRE
Journal :
Journal of Contemporary Brachytherapy
Accession number :
edsair.doi.dedup.....76f80e88d5d334348d49167417b90874