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Developmental profiles of childhood attention-deficit/hyperactivity disorder and irritability: association with adolescent mental health, functional impairment, and suicidal outcomes
- Source :
- Journal of Child Psychology and Psychiatry, Journal of Child Psychology and Psychiatry, Wiley, In press, ⟨10.1111/jcpp.13270⟩, Journal of Child Psychology and Psychiatry, In press, ⟨10.1111/jcpp.13270⟩
- Publication Year :
- 2020
-
Abstract
- International audience; Background: Irritability is frequently comorbid with ADHD. Although irritability alone has been linked to deleterious mental health and adaptive issues, the joint developmental course of ADHD and irritability symptoms during childhood as well as its association with later mental health and suicidal outcomes is not fully understood. We aimed to describe the developmental trajectories of childhood ADHD and irritability symptoms and to quantify their association with adolescent mental health and suicidal outcomes.Methods: The Quebec Longitudinal Study of Child Development (QLSCD) included 1407 participants from the general population followed up from age 5 months to 17 years. We used a multitrajectory approach to identify developmental trajectories of childhood (6-12 years) ADHD and irritability symptoms. Outcome measures were adolescent (13-17 years) mental health (psychiatric symptoms/functional impairment) and suicidal outcomes.Results: We identified distinct developmental profiles: combined absent or very low ADHD and absent or very low irritability (940 [66.8%]; reference group), moderately high irritability and low ADHD (158 [11.2%]), moderately high ADHD and low irritability (198 [14.1%]), and combined high ADHD and high irritability (111 [7.9%]). Multivariate modeling showed that, compared to children in the reference group, those in the combined high ADHD and high irritability profile showed higher levels of ADHD continuity (d ranges = 0.40-0.50), externalizing (d ranges = 0.25-0.59), internalizing (d ranges = 0.20-0.29), and functional impairments (d ranges = 0.17-0.48) and suicidal behaviors (odds ratio (OR) = 2.12, confidence interval (CI) = 1.47-3.06) in adolescence.Conclusions: The presence of persistently high levels of irritability along with ADHD symptoms during childhood significantly predicts adolescent ADHD continuity, externalizing, internalizing, and suicidal outcomes. Systematic consideration of irritability when assessing and treating ADHD may improve long-term mental health outcomes.
- Subjects :
- Longitudinal study
Adolescent
Population
[SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health
Poison control
Irritability
Suicidal Ideation
03 medical and health sciences
0302 clinical medicine
[SDV.MHEP.PED] Life Sciences [q-bio]/Human health and pathology/Pediatrics
Injury prevention
mental disorders
Developmental and Educational Psychology
medicine
Attention deficit hyperactivity disorder
Humans
0501 psychology and cognitive sciences
Longitudinal Studies
education
Child
education.field_of_study
[SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatrics
05 social sciences
Infant, Newborn
medicine.disease
Child development
Mental health
Irritable Mood
3. Good health
Psychiatry and Mental health
Mental Health
Attention Deficit Disorder with Hyperactivity
[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health
Pediatrics, Perinatology and Child Health
medicine.symptom
Psychology
030217 neurology & neurosurgery
050104 developmental & child psychology
Clinical psychology
Subjects
Details
- Language :
- English
- ISSN :
- 00219630 and 14697610
- Database :
- OpenAIRE
- Journal :
- Journal of Child Psychology and Psychiatry, Journal of Child Psychology and Psychiatry, Wiley, In press, ⟨10.1111/jcpp.13270⟩, Journal of Child Psychology and Psychiatry, In press, ⟨10.1111/jcpp.13270⟩
- Accession number :
- edsair.doi.dedup.....772948471fbb7f6c1a220e1c40dc3f67