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Association between Healthy Eating Index-2015 and Breast Cancer Risk: A Case-Control Study
- Source :
- Asian Pacific Journal of Cancer Prevention : APJCP
- Publication Year :
- 2020
-
Abstract
- Objective Diet quality is known to influence cancer risk. The Healthy Eating Index (HEI) is one of the most frequently used measures of diet quality. However, the association between HEI-2015 and breast cancer risk is not known. The present study was undertaken to evaluate the association between HEI-2015 and breast cancer risk. Methods A case-control study comprising 134 breast cancer patients and 265 cancer-free controls were conducted. Dietary intakes were assessed using a validated food frequency questionnaire (FFQ), from which the HEI-2015 score was calculated. Logistic regression was used to derive the odds ratios (ORs) for measuring the association between HEI-2015 scores and breast cancer risk. Results Subjects in the top quartile of HEI-2015 had a 46% lower chance of breast cancer compared with subjects in the bottom quartile (OR 0.54; 95% CI 0.30, 0.98). After adjustment for potential confounders such as age, age at menarche, oral contraceptive drug use, menopausal status, marital status, body mass index, smoking and education level, the association between HEI-2015 score and a lower risk of breast cancer was enhanced (OR 0.32; 95% CI 0.16, 0.65). Conclusion We successfully demonstrated that a higher HEI-2015 score was associated with a reduced breast cancer risk.
- Subjects :
- 0301 basic medicine
Adult
Healthy Eating Index-2015
medicine.medical_specialty
Breast Neoplasms
Lower risk
Body Mass Index
03 medical and health sciences
0302 clinical medicine
Breast cancer
breast cancer
Internal medicine
Medicine
Humans
Aged
business.industry
Confounding
Case-control study
General Medicine
Odds ratio
Middle Aged
medicine.disease
Prognosis
030104 developmental biology
Quartile
030220 oncology & carcinogenesis
Case-Control Studies
Menarche
Educational Status
Female
Diet, Healthy
business
diet
Body mass index
Follow-Up Studies
Research Article
Subjects
Details
- ISSN :
- 2476762X
- Volume :
- 21
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Asian Pacific journal of cancer prevention : APJCP
- Accession number :
- edsair.doi.dedup.....7731fa3e2beac83791073b4cf6c899c3