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Suppl. Figure 9 from Identification of CRKII, CFL1, CNTN1, NME2, and TKT as Novel and Frequent T-Cell Targets in Human IDH-Mutant Glioma

Authors :
Christel Herold-Mende
Philipp Beckhove
Andreas Unterberg
Andreas von Deimling
Markus A. Weigand
Christoph Schramm
Niels Grabe
Volker Eckstein
Uwe Warnken
Christine Jungk
Saskia Roesch
Kolja Pocha
David Reuss
Anchana Rathinasamy
Carmen Rapp
Martina Schnölzer
Rolf Warta
Slava Stamova
Steffen Dettling
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

(A) IFN-� ELISpot raw data of all HLA-A*02:01 patients analyzed (n = 7) showing the IFN-� spots / 1x105 T-cells for patient cells against TAAs vs. patient cells against the negative control (human immunodeficiency virus (HIV) gag/pol, 9 amino acids). Grey bars indicate a significantly increased immunogenicity compared to negative control (solid line). (B) Homogenous levels of stimulation while comparing the total immune response by mean of IFN-� spot numbers among astrocytomas (red) and oligodendrogliomas (blue) to a certain reactive epitope. (n.s., not significant, *, p < 0.05; **, p < 0.01)

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....779e4ea1c6c2868c22a3ea42c9a9dede
Full Text :
https://doi.org/10.1158/1078-0432.22465494