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Additional file 3 of Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neurons

Authors :
Andries, Lien
Kancheva, Daliya
Masin, Luca
Scheyltjens, Isabelle
Van Hove, Hannah
De Vlaminck, Karen
Bergmans, Steven
Claes, Marie
De Groef, Lies
Moons, Lieve
Movahedi, Kiavash
Publication Year :
2023
Publisher :
figshare, 2023.

Abstract

Additional file 3. Full scRNA-seq dataset of naïve, ONC and ONC+P3C CD11b+CD45+ cells. A UMAP and cluster annotation showing 22081 cells of both healthy, injuredand regeneratingretinas. BAM, border associated macrophage, cDC: conventional dendritic cell, migDC: migratory dendritic cell, MDM: monocyte-derived macrophage, Mg: microglia, MO, monocyte, N: neutrophils, NK: natural killer cell. B,C UMAP showing 6997 cells of retinas at 4dpi ONC+P3Cand 7956 cells of retinas at 8dpi ONC+P3C. Individual pie charts show the distribution of neutrophils, monocytes or alle immune populations. Numbers in the pie chart are percentages of the cells from the corresponding cluster.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....77a3b72c8dddca1b6f2cc76db7f154e1
Full Text :
https://doi.org/10.6084/m9.figshare.23167825