Back to Search
Start Over
Mesalamine-induced eosinophilic pleural effusion
- Source :
- BMJ Case Rep
- Publication Year :
- 2020
-
Abstract
- A 45-year-old woman with a medical history of ulcerative colitis (UC) presented with difficulty in breathing. The patient was diagnosed with UC a month prior to presentation and was started on mesalamine suppository. Chest x-ray (CXR) on presentation showed bilateral pleural effusion, which was confirmed on CT angiogram of the chest. Diagnostic and therapeutic thoracentesis was performed and 0.7 L of pleural fluid was removed from the left side. The pleural fluid analysis was consistent with exudative pleural effusion with eosinophilia. Symptomatic improvement was noted after thoracentesis. Mesalamine was stopped and repeat CXR was obtained on the follow-up visit, which showed no pleural effusion. The Naranjo score was calculated to be 7, indicating that the eosinophilic pleural effusion was most probably secondary to adverse reaction from mesalamine.
- Subjects :
- medicine.medical_specialty
Pleural effusion
medicine.medical_treatment
Thoracentesis
030204 cardiovascular system & hematology
Suppository
Diagnosis, Differential
03 medical and health sciences
0302 clinical medicine
Eosinophilic
Eosinophilia
medicine
Humans
Medical history
Mesalamine
Unexpected Outcome (Positive or Negative) Including Adverse Drug Reactions
business.industry
Anti-Inflammatory Agents, Non-Steroidal
General Medicine
respiratory system
Middle Aged
medicine.disease
Ulcerative colitis
Exudative pleural effusion
respiratory tract diseases
Pleural Effusion
Colitis, Ulcerative
Female
Radiology
medicine.symptom
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 1757790X
- Volume :
- 13
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- BMJ case reports
- Accession number :
- edsair.doi.dedup.....77c7346310de7d06b4292b9faa748d20