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Supplementary Materials and Methods, Figures, Figure Legends - Revised from The Histone Methyltransferase DOT1L Promotes Neuroblastoma by Regulating Gene Transcription

Authors :
Tao Liu
Christopher J. Scarlett
Giovanni Perini
Patsie Polly
Jenny Wang
Jason W.H. Wong
Stefan Hüttelmaier
Xu Dong Zhang
Pei Yan Liu
Dora Ling
Nicholas Ho
Duohui Jing
Yuting Sun
Bernard Atmadibrata
Rebecca C. Poulos
Jessica L. Bell
Giorgio Milazzo
Andrew E.L. Tee
Matthew Wong
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplementary Materials and Methods, Figures, Figure Legends. Fig. S1, N-Myc up-regulates ODC1 and E2F2. Fig. S2, DOT1L and N-Myc do not regulate HIF1α and VEGF. Fig. S3, knocking down DOT1L gene expression does not induce neuroblastoma cell death. Fig. S4, knocking down DOT1L reduces ODC1 and E2F2 expression in neuroblastoma tissues in mice. Fig. S5, DOT1L expression correlates with ODC1 and E2F2 expression in human neuroblastoma tissues.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....783a62e881eb9b3fc669278845031d96
Full Text :
https://doi.org/10.1158/0008-5472.22416506